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Components

Ipakitine is a complete and optimised combination of chitosan and calcium carbonate. Both substances play their role in binding phosphates. In addition chitosan binds some uraemic toxins which cause many of the clinical symptoms.
Years of use in the field has confirmed the very high palatability of Ipakitine. This is of  particular importance in the case of CRF and especially for cats.

 

Components


Calcium carbonate: the phosphate eliminator agent

Calcium carbonate belongs to the short list of substances commonly used in human medicine to bind phosphate in patients with CRF:

 

Intestinal phosphorus binding agents

Approximate daily
Recommended dose

•  Aluminium hydroxide
•  Aluminium carbonate
•  Aluminium oxide
•  Calcium carbonate

30 to 90mg/kg/d
30 to 90mg/kg/d
30 to 90mg/kg/d
90 to 150mg/kg/d


Calcium carbonate is safe. It is not an aluminium based phosphorus binding agent. Aluminium accumulates in various tissues of the body including bones and brain and may lead to encephalopathy, anaemia, bone disease…


Chitosan : the reno-protective agent

Chitosan results from the de-acetylation of the chitin of crabs. There are many different types of chitosan according to their molecular weight and de-acetylation rate.

 Chitosan has been proven to decrease blood urea and creatinine in rats, mice and human. It decreases blood phosphorus and urea in cats and binds numerous uraemic toxins, in vitro.